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KMID : 0378019800230120059
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New Medical Journal
1980 Volume.23 No. 12 p.59 ~ p.62
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FSH Cells in the Adenohypophysis of Human Fetus as Revealed by Immunohistochemistry
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Abstract
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Nine human fetal adenohypophyses ranging 13-20 weeks in gestational age were studied immunohistochemically to demonstrate follicle stimulating hormone cells.
Pituitary glands and adjoining tissues were excised and fixed in Bouin´s fluid and serial sections were made at 5u. The tissue sections were reacted with rabbit antiserum to human follicle stimulating hormone, and then with peroxidase lableled sheep antirabbit gamma globulin, followed by enzyme staining.
The observation performed under light microscope were summarized as follows.
1. FSH cells occured first at 16 weeks, but no FSH cell was demonstrable before 16 weeks.
2. Reacting intesities of cytoplasmic granules generally increased with advancing fetal age.
3. Upon first appearing in the pars distalis FSH cells were found chiefly in the anterosuperior region, and became widely distributed in the pars distalis with advancing age.
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KEYWORD
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